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1

Formation and biochemistry of carcinogenic heterocyclic aromatic amines in cooked meats

Robert J. Turesky

Journal:

Toxicology Letters

Year:

2007

Language:

english

File:

PDF, 602 KB

english, 2007

2

The effects of coffee on enzymes involved in metabolism of the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in rats

Robert J. Turesky, Janique Richoz, Anne Constable, Kellie D. Curtis, Karen H. Dingley, Kenneth W. Turteltaub

Journal:

Chemico-Biological Interactions

Year:

2003

Language:

english

File:

PDF, 348 KB

english, 2003

3

Oxidation of Caffeine and Related Methylxanthines in Ascorbate and Polyphenol-Driven Fenton-Type Oxidations

Stadler, Richard H., Richoz, Janique, Turesky, Robert J., Welti, Dieter H., Fay, Laurent B.

Journal:

Free Radical Research

Year:

1996

Language:

english

File:

PDF, 1.38 MB

english, 1996

4

A Method for Biomonitoring of DNA Adducts in Exfoliated Urinary Cells by Mass Spectrometry

Yun, Byeong Hwa, Bellamri, Medjda, Rosenquist, Thomas A., Turesky, Robert J

Journal:

Analytical Chemistry

Year:

2018

Language:

english

File:

PDF, 1.38 MB

english, 2018

5

Genetic and epigenetic regulation of AHR gene expression in MCF-7 breast cancer cells: Role of the proximal promoter GC-rich region

Neal A. Englert, Robert J. Turesky, Weiguo Han, Erin E. Bessette, Simon D. Spivack, Michele Caggana, David C. Spink, Barbara C. Spink

Journal:

Biochemical Pharmacology

Year:

2012

Language:

english

File:

PDF, 1.04 MB

english, 2012

6

Identification of Aminobiphenyl Derivatives in Commercial Hair Dyes

Turesky, Robert J., Freeman, James P., Holland, Ricky D., Nestorick, Daniel M., Miller, Dwight W., Ratnasinghe, D. Luke, Kadlubar, Fred F.

Journal:

Chemical Research in Toxicology

Year:

2003

Language:

english

File:

PDF, 203 KB

english, 2003

7

The coffee components kahweol and cafestol induce γ-glutamylcysteine synthetase, the rate limiting enzyme of chemoprotective glutathione synthesis, in several organs of the rat

Wolfgang W. Huber, Gerlinde Scharf, Walter Rossmanith, Sonja Prustomersky, Bettina Grasl-Kraupp, Barbara Peter, Robert J. Turesky, Rolf Schulte-Hermann

Journal:

Archives of Toxicology

Year:

2002

Language:

english

File:

PDF, 196 KB

english, 2002

8

Comparison of DNA-adduct and tissue-available dose levels of MeIQx in human and rodent colon following administration of a very low dose

Robert J. Mauthe, Karen H. Dingley, Steven H. Leveson, Stewart P.H.T. Freeman, Robert J. Turesky, R. Colin Garner, Kenneth W. Turteltaub

Journal:

International Journal of Cancer

Year:

1999

Language:

english

File:

PDF, 96 KB

english, 1999

9

Interspecies metabolism of heterocyclic aromatic amines and the uncertainties in extrapolation of animal toxicity data for human risk assessment

Robert J. Turesky

Journal:

Molecular Nutrition & Food Research

Year:

2005

Language:

english

File:

PDF, 2.52 MB

english, 2005

10

Formation and analysis of heterocyclic aromatic amine–DNA adducts in vitro and in vivo

Robert J. Turesky, Paul Vouros

Journal:

Journal of Chromatography B

Year:

2004

Language:

english

File:

PDF, 435 KB

english, 2004

11

Interspecies differences in metabolism of heterocyclic aromatic amines by rat and human P450 1A2

Robert J. Turesky, Anne Constable, Laurent B. Fay, F.Peter Guengerich

Journal:

Year:

1999

Language:

english

File:

PDF, 146 KB

english, 1999

12

The contribution of N-oxidation to the metabolism of the food-borne carcinogen 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in rat hepatocytes

Turesky, Robert J., Bracco-Hammer, Ingrid, Markovic, Jovanka, Richli, Urs, Kappeler, Anne Marie, Welti, Dieter H.

Journal:

Chemical Research in Toxicology

Year:

1990

Language:

english

File:

PDF, 1.45 MB

english, 1990

13

Formalin-Fixed Paraffin-Embedded Tissues—An Untapped Biospecimen for Biomonitoring DNA Adducts by Mass Spectrometry

Yun, Byeong, Guo, Jingshu, Turesky, Robert

Journal:

Year:

2018

Language:

english

File:

PDF, 3.63 MB

english, 2018

14

Development of a DNA Adductome Mass Spectral Database

Guo, Jingshu, Turesky, Robert J., Tarifa, Anamary, DeCaprio, Anthony P., Cooke, Marcus S., Walmsley, Scott J., Villalta, Peter W.

Journal:

Chemical Research in Toxicology

Year:

2020

File:

PDF, 3.84 MB

2020

15

Metabolism and Biomarkers of Heterocyclic Aromatic Amines in Molecular Epidemiology Studies: Lessons Learned from Aromatic Amines

Turesky, Robert J., Le Marchand, Loic

Journal:

Chemical Research in Toxicology

Year:

2011

Language:

english

File:

PDF, 2.01 MB

english, 2011

16

Determination of Apurinic/Apyrimidinic Lesions in DNA with High-Performance Liquid Chromatography and Tandem Mass Spectrometry

Roberts, Kenneth P., Sobrino, Justin A., Payton, Julie, Mason, Lavinnia B., Turesky, Robert J.

Journal:

Chemical Research in Toxicology

Year:

2006

Language:

english

File:

PDF, 160 KB

english, 2006

17

Screening for DNA Adducts by Data-Dependent Constant Neutral Loss-Triple Stage Mass Spectrometry with a Linear Quadrupole Ion Trap Mass Spectrometer

Bessette, Erin E., Goodenough, Angela K., Langouët, Sophie, Yasa, Isil, Kozekov, Ivan D., Spivack, Simon D., Turesky, Robert J.

Journal:

Analytical Chemistry

Year:

2009

Language:

english

File:

PDF, 283 KB

english, 2009

18

Sulfamate formation is a major route for detoxification of 2-amino-3-methylimidazo[4, 5-f]quinoline in the rat

Turesky, Robert J., Skipper, Paul L., Tannenbaum, Steven R., Coles, Brian, Ketterer, Brian

Journal:

Year:

1986

Language:

english

File:

PDF, 289 KB

english, 1986

19

Identification of 2-Amino-1,7-dimethylimidazo[4,5- g ]quinoxaline: An Abundant Mutagenic Heterocyclic Aromatic Amine Formed in Cooked Beef

Turesky, Robert J., Goodenough, Angela K., Ni, Weijuan, McNaughton, Lynn, LeMaster, David M., Holland, Ricky D., Wu, Rebekah W., Felton, James S.

Journal:

Chemical Research in Toxicology

Year:

2007

Language:

english

File:

PDF, 608 KB

english, 2007

20

Novel LC-ESI/MS/MS n Method for the Characterization and Quantification of 2‘-Deoxyguanosine Adducts of the Dietary Carcinogen 2-Amino-1-methyl-6-phenylimidazo[4,5- b ]pyridine by 2-D Linear Quadrupole Ion Trap Mass Spectrometry

Goodenough, Angela K., Schut, Herman A. J., Turesky, Robert J.

Journal:

Chemical Research in Toxicology

Year:

2007

Language:

english

File:

PDF, 461 KB

english, 2007

21

Formation and Differential Removal of C-8 and N 2 -Guanine Adducts of the Food Carcinogen 2-Amino-3-methylimidazo[4,5- f ]quinoline in the Liver, Kidney, and Colorectum of the Rat

Turesky, Robert J., Markovic, Jovanka, Aeschlimann, Jean-Marc

Journal:

Chemical Research in Toxicology

Year:

1996

Language:

english

File:

PDF, 247 KB

english, 1996

22

Introduction: Gene-Environmental Interactions in Molecular Epidemiology; Gene-Environment Interactions;

KADLUBAR, FRED, GORLEWSKA, KASIA, GREEN, BRIDGETT, TURESKY, ROBERT, HUNTER, DAVID

Journal:

Toxicologic Pathology

Year:

2004

Language:

english

File:

PDF, 29 KB

english, 2004

23

Aristolochic acid exposure in Romania and implications for renal cell carcinoma

Turesky, Robert J, Yun, Byeong Hwa, Brennan, Paul, Mates, Dana, Jinga, Viorel, Harnden, Patricia, Banks, Rosamonde E, Blanche, Helene, Bihoreau, Marie-Therese, Chopard, Priscilia, Letourneau, Louis, L

Journal:

British Journal of Cancer

Year:

2015

Language:

english

File:

PDF, 645 KB

english, 2015

24

Targeted and Untargeted Detection of DNA Adducts of Aromatic Amine Carcinogens in Human Bladder by Ultra Performance Liquid Chromatography-High Resolution Mass Spectrometry

Guo, Jingshu, Villalta, Peter W., Weight, Christopher J., Bonala, Radha, Johnson, Francis, Rosenquist, Thomas A., Turesky, Robert J

Journal:

Chemical Research in Toxicology

Year:

2018

Language:

english

File:

PDF, 2.04 MB

english, 2018

25

Comparison of Gas Chromatography–Mass Spectrometry and Liquid Chromatography–Tandem Mass Spectrometry Methods to Quantify α-Tocopherol and α-Tocopherolquinone Levels in Human Plasma

Pascal Mottier, Eric Gremaud, Philippe A. Guy, Robert J. Turesky

Journal:

Analytical Biochemistry

Year:

2002

Language:

english

File:

PDF, 105 KB

english, 2002

26

Inter-individual differences in the metabolism of environmental toxicants: cytochrome P450 1A2 as a prototype

F.Peter Guengerich, Asit Parikh, Robert J. Turesky, P.David Josephy

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

1999

Language:

english

File:

PDF, 354 KB

english, 1999

27

Metabolism of the Food-Borne Mutagen 2-Amino-3,8-dimethylimidazo[4,5- f ]quinoxaline in Humans

Turesky, Robert J., Garner, R. Colin, Welti, Dieter H., Richoz, Janique, Leveson, Steve H., Dingley, Karen H., Turteltaub, Kenneth W., Fay, Laurent B.

Journal:

Chemical Research in Toxicology

Year:

1998

Language:

english

File:

PDF, 124 KB

english, 1998

28

Neuromelanin modulates heterocyclic aromatic amine-induced dopaminergic neurotoxicity

Lawana, Vivek, Um, Se Young, Rochet, Jean-Christophe, Turesky, Robert J, Shannahan, Jonathan H, Cannon, Jason R

Journal:

Toxicological Sciences

Year:

2019

Language:

english

File:

PDF, 4.52 MB

english, 2019

29

Macromolecular adduct formation and metabolism of heterocyclic amines in humans and rodents at low doses

Kenneth W Turteltaub, Karen H Dingley, Kellie D Curtis, Michael A Malfatti, Robert J Turesky, R Colin Garner, James S Felton, Nicholas P Lang

Journal:

Year:

1999

Language:

english

File:

PDF, 170 KB

english, 1999

30

Metabolism of 2-Amino-3,8-dimethylimidazo[4,5- f ]- quinoxaline in Human Hepatocytes: 2-Amino-3-methylimidazo[4,5- f ]quinoxaline-8-carboxylic Acid Is a Major Detoxication Pathway Catalyzed by Cytochrome P450 1A2

Langouët, Sophie, Welti, Dieter H., Kerriguy, Nathalie, Fay, Laurent B., Huynh-Ba, Tuong, Markovic, Jovanka, Guengerich, F. Peter, Guillouzo, André, Turesky, Robert J.

Journal:

Chemical Research in Toxicology

Year:

2001

Language:

english

File:

PDF, 125 KB

english, 2001

31

Supplement 6: Carcinogenic and Mutagenic N-Substituted Aryl Compounds || Species Differences in Metabolism of Heterocyclic Aromatic Amines, Human Exposure, and Biomonitoring

Robert J. Turesky, Gian A. Gross, W. G. Stillwell, Paul L. Skipper and Steven R. Tannenbaum

Journal:

Environmental Health Perspectives

Year:

1994

Language:

english

File:

PDF, 1.05 MB

english, 1994

32

The Impact of NAT2 Acetylator Genotype on Mutagenesis and DNA Adducts from 2-Amino-9 H -pyrido[2,3- b ]indole

Turesky, Robert J., Bendaly, Jean, Yasa, Isil, Doll, Mark A., Hein, David W.

Journal:

Chemical Research in Toxicology

Year:

2009

Language:

english

File:

PDF, 765 KB

english, 2009

33

Binding of 2-amino-3-methylimidazo[4,5-f]quinoline to hemoglobin and albumin in vivo in the rat. Identification of an adduct suitable for dosimetry

Turesky, Robert J., Skipper, Paul L., Tannenbaum, Steven R.

Journal:

Year:

1987

Language:

english

File:

PDF, 666 KB

english, 1987

34

Qualitative and quantitative characterization of mutagens in commercial beef extract

Turesky, Robert J., Wishnok, John S., Tannenbaum, Steven R., Pfund, Rolland A., Buchi, George H.

Journal:

Year:

1983

Language:

english

File:

PDF, 361 KB

english, 1983

35

Purification of the food-borne carcinogens 2-amino-3-methylimidazo [4,5- f ]quinoline and 2-amino-3,8-dimethylimidazo[4,5- f ]quinoxaline in heated meat products by immunoaffinity chromatography

Turesky, Robert J., Forster, Christina M., Aeschbacher, Hans Ulrich, Würzner, Hans Peter, Skipper, Paul L., Trudel, Laura J., Tannenbaum, Steven R.

Journal:

Year:

1989

Language:

english

File:

PDF, 619 KB

english, 1989

36

Formation of DNA adducts by the food mutagen 2-amino-3,4,8-trimethyl-3 H -imidazo [4,8- f ]quinoxaline (4,8-DiMeIQx) in vitro and in vivo . Identification of a N -(2′-deoxyguanosin-8-yl)-4,8-DiMeIQx adduct

Frandsen, Henrik, Grivas, Spiros, Turesky, Robert J., Andersson, Rolf, Dragsted, Lars O., Larsen, John C.

Journal:

Year:

1994

Language:

english

File:

PDF, 872 KB

english, 1994

37

Measurement of the Heterocyclic Amines 2-Amino-9 H -pyrido[2,3- b ]indole and 2-Amino-1-methyl-6-phenylimidazo[4,5- b ]pyridine in Urine: Effects of Cigarette Smoking

Konorev, Dmitri, Koopmeiners, Joseph S., Tang, Yijin, Franck Thompson, Elizabeth A., Jensen, Joni A., Hatsukami, Dorothy K., Turesky, Robert J.

Journal:

Chemical Research in Toxicology

Year:

2015

Language:

english

File:

PDF, 2.18 MB

english, 2015

38

DNA adducts: Formation, biological effects, and new biospecimens for mass spectrometric measurements in humans

Hwa Yun, Byeong, Guo, Jingshu, Bellamri, Medjda, Turesky, Robert J.

Journal:

Mass Spectrometry Reviews

Year:

2018

Language:

english

File:

PDF, 3.83 MB

english, 2018

39

Capturing Labile Sulfenamide and Sulfinamide Serum Albumin Adducts of Carcinogenic Arylamines by Chemical Oxidation

Peng, Lijuan, Turesky, Robert J.

Journal:

Analytical Chemistry

Year:

2013

Language:

english

File:

PDF, 964 KB

english, 2013

40

Determination of in Vitro- and in Vivo-Formed DNA Adducts of 2-Amino-3-methylimidazo[4,5- f ]quinoline by Capillary Liquid Chromatography/Microelectrospray Mass Spectrometry

Gangl, Eric T., Turesky, Robert J., Vouros, Paul

Journal:

Chemical Research in Toxicology

Year:

1999

Language:

english

File:

PDF, 263 KB

english, 1999

41

Formation of Deoxyguanosine Cross-Links from Calf Thymus DNA Treated with Acrolein and 4-Hydroxy-2-nonenal

Kozekov, Ivan D., Turesky, Robert J., Alas, Guillermo R., Harris, Constance M., Harris, Thomas M., Rizzo, Carmelo J.

Journal:

Chemical Research in Toxicology

Year:

2010

Language:

english

File:

PDF, 2.50 MB

english, 2010

42

Mass Spectrometric Characterization of Human Serum Albumin Adducts Formed with N-Oxidized Metabolites of 2-Amino-1-methylphenylimidazo[4,5- b ]pyridine in Human Plasma and Hepatocytes

Wang, Yi, Peng, Lijuan, Bellamri, Medjda, Langouët, Sophie, Turesky, Robert J.

Journal:

Chemical Research in Toxicology

Year:

2015

Language:

english

File:

PDF, 2.58 MB

english, 2015

43

2-Bromo-5-fluorobenzaldehyde

Tureski, Robert E., Tanski, Joseph M.

Journal:

Acta Crystallographica Section E Structure Reports Online

Year:

2013

Language:

english

File:

PDF, 347 KB

english, 2013

44

A Comprehensive Approach to the Profiling of the Cooked Meat Carcinogens 2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline, 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, and Their Metabolites in Human Urine

Gu, Dan, McNaughton, Lynn, LeMaster, David, Lake, Brian G., Gooderham, Nigel J., Kadlubar, Fred F., Turesky, Robert J.

Journal:

Chemical Research in Toxicology

Year:

2010

Language:

english

File:

PDF, 2.60 MB

english, 2010

45

Metabolism of Ochratoxin A: Absence of Formation of Genotoxic Derivatives by Human and Rat Enzymes

Gautier, Jean-Charles, Richoz, Janique, Welti, Dieter H., Markovic, Jovanka, Gremaud, Eric, Guengerich, F. Peter, Turesky, Robert J.

Journal:

Chemical Research in Toxicology

Year:

2001

Language:

english

File:

PDF, 197 KB

english, 2001

46

Biomonitoring of 2-Amino-1-methyl-6-phenylimidazo[4,5- b ]pyridine (PhIP) and Its Carcinogenic Metabolites in Urine

Fede, Jean-Marie, Thakur, Anup P., Gooderham, Nigel J., Turesky, Robert J.

Journal:

Chemical Research in Toxicology

Year:

2009

Language:

english

File:

PDF, 1.06 MB

english, 2009

47

DNA adduct formation of the food carcinogen 2-amino-3-methylimidazo[4, 5- f ]quinoline (IQ) in liver, kidney and colo-rectum of rats

Turesky, Robert J., Markovic, Jovanka

Journal:

Year:

1995

Language:

english

File:

PDF, 1.96 MB

english, 1995

48

Dose validation of PhIP hair level as a biomarker of heterocyclic aromatic amines exposure: a feeding study

Le Marchand, Loïc, Yonemori, Kim, White, Kami K., Franke, Adrian A., Wilkens, Lynne R., Turesky, Robert J.

Journal:

Year:

2016

Language:

english

File:

PDF, 745 KB

english, 2016

49

Ultraperformance Liquid Chromatography−Tandem Mass Spectrometry Method for Biomonitoring Cooked Meat Carcinogens and Their Metabolites in Human Urine

Gu, Dan, Raymundo, Melissa M., Kadlubar, Fred F., Turesky, Robert J.

Journal:

Analytical Chemistry

Year:

2011

Language:

english

File:

PDF, 1.97 MB

english, 2011

50

Identification of N-(deoxyguanosin-8-yl)-2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine as the major adduct formed by the food-borne carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, with DNA

Lin, Dongxin, Kaderlik, Keith R., Turesky, Robert J., Miller, Dwight W., Lay, Jackson O., Kadlubar, Fred F.

Journal:

Chemical Research in Toxicology

Year:

1992

Language:

english

File:

PDF, 1.32 MB

english, 1992

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